Encompass Ophthalmic Development, Inc. recently announced it has secured the exclusive worldwide ophthalmic rights to PROLOC Bioadhesive Ocular Drug Delivery System from the Transdermal and Transmucosal business of Henkel Corporation. 

PROLOC features long-lasting drug release and high bioavailability compared to traditional eye drops, ointments, and gels. It is a preservative-free polymer matrix in uniquely formed ocular mini-tablet form that is applied to the fornix. Upon insertion, PROLOC adheres rapidly to the ocular mucosa and transforms to a comfortable gel-like substance that will remain in place until fully eroded.

The PROLOC Bioadhesive Ocular Drug Delivery System permits high active ingredient loading and is compatible with hydrophilic or lipophilic active ingredients. PROLOC Bioadhesives are capable of residing over 8 hours during which time the active drug is gradually released. PROLOC is manufactured using USP ingredients, and clinical studies have been conducted to support ocular use.

The increased time that PROLOC remains in the eye may allow for lower concentrations of a drug to be administered over a longer period of time. This minimizes the inconvenience of frequent dosing, reduces the potential of related adverse side effects, and may lead to improved patient compliance.

The technology offers intellectual property protection, provides the opportunity to expand the lifecycle of current branded drugs, and opens new possibilities for new drug molecules and uniquely delivered therapies.

Encompass Development, Inc. is an Atlanta-based company focused on the development and out-licensing of ophthalmic pharmaceuticals and drug delivery systems. Encompass Pharmaceutical Services, Inc provides a full range of analytical, stability, and consulting services for the global pharmaceutical industry. One of its core competencies is ophthalmic development and formulation services from preformulation through manufacturing scale-up and quality systems. Services include preclinical support, drug formulation, drug delivery development, clinical supplies, and manufacturing support. 

source：web of drug delivery tech