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University Of Greenwich Forges Ahead In Research On Drug delivery To Organelles
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- Publication：2010/3/1
A team of scientists at The University of Greenwich claimedPBR that it has inched a step closer in finding a vehicle that can carry drugs not just to a specific cell but a specific organ (organelle) inside the cell, and accurately measure how it behaves when it gets there.
According to Journal of Controlled Release, Dr Simon Richardson and his colleagues provided direct evidence that nanomedicines can be delivered to chosen organelles and manipulated to carry beneficial agents like genes.
The research team was also able to show how the delivery carrier acts once it is inside.
According to professor Kinam Park, editor of the Journal of Controlled Release, the study was 'distinguished from others by its thoroughness and unequivocal data.
Mr Kinam Park said: “The approach used by Richardson’s team can be useful in developing more efficient delivery vehicles for drug targeting in general.”
Dr Richardson said: “Drug delivery is important for everyone because it has the potential to deliver new treatments for diseases which are currently incurable; and to deliver existing drugs more effectively. We are trying to smuggle healthy genes inside cells. Genes are large molecules which have up till now proved too big to get in without serious risk to the patient.
“Our research is at the cutting edge of efforts to turn gene therapy, and new molecular medicines, from risky and sci-fiesque to safe and routine.”
Source：web of PBR